Lipid Metabolism

Cholesterol to bile acids via 7-alpha-hydroxylase, the rate-limiting step

A memory aid for bile acid production and its regulation.

Chylomicrons carry dietary fat, VLDL endogenous fat, LDL delivers cholesterol, HDL returns it

A memory aid for the lipoprotein classes and their roles.

Acetyl-CoA to mevalonate via HMG-CoA reductase, the rate-limiting step

A memory aid for the cholesterol synthetic pathway and its regulation.

Cyclo-oxygenase makes prostaglandins; lipoxygenase makes leukotrienes

A memory aid for the arachidonic acid pathways.

Saturated, monounsaturated and polyunsaturated, with omega-3 and omega-6 essential

A memory aid for the types of dietary fatty acid.

Carnitine shuttles long chain fatty acids into mitochondria for beta oxidation

A memory aid for beta oxidation and its requirements.

Cytoplasmic synthesis from acetyl-CoA using NADPH, with acetyl-CoA carboxylase rate limiting

A memory aid for how fatty acids are made.

Made in the liver from acetyl-CoA, used by brain, heart and muscle

A memory aid for ketone production and use.

Hormone sensitive lipase releases it, albumin carries it, carnitine admits it

A memory aid for how stored fat is mobilised and transported.