Mnemonic

Ossification and the Growth Plate

A memory aid for how bone forms and grows in length.

Expansion

Intramembranous for flat bones, endochondral for long bones

Expansion

Two types of ossification

  • Intramembranous: bone forms directly from mesenchyme. The flat bones of the skull, the clavicle and the mandible
  • Endochondral: bone replaces a cartilage model. All long bones, the base of the skull and the vertebrae

Growth plate (physis) zones, from epiphysis to diaphysis:

  1. Resting (reserve) cartilage
  2. Proliferative - chondrocytes divide and stack in columns
  3. Hypertrophic - chondrocytes enlarge. The weakest zone, and where fractures and slipped upper femoral epiphysis occur
  4. Calcification
  5. Ossification - vascular invasion and bone deposition

“Growth in length at the physis, growth in width from the periosteum.”

Salter-Harris classification of physeal fractures, SALTR:

  • I - Straight across the physis
  • II - Above, into the metaphysis. The commonest
  • III - beLow, into the epiphysis
  • IV - Through both
  • V - cRush injury. The worst prognosis and often diagnosed retrospectively

Types III to V involve the joint surface or crush the plate, so they risk growth arrest and deformity, which is why they need accurate reduction and follow-up.