Mnemonic

Peritoneal Fluid Circulation

A memory aid for how fluid moves within the peritoneal cavity.

Expansion

Fluid moves upwards towards the diaphragm and is absorbed through diaphragmatic lymphatics

Expansion

The peritoneal cavity normally contains only about 50 ml of serous fluid, but there is a continuous circulation:

  • Secreted by the peritoneal mesothelium
  • Moved upwards along the paracolic gutters towards the diaphragm by the negative pressure generated on inspiration
  • Absorbed through specialised stomata in the diaphragmatic peritoneum into subdiaphragmatic lymphatics, and thence to the mediastinal nodes and thoracic duct

This explains several clinical patterns:

  • Subphrenic abscess following lower abdominal sepsis, since fluid travels up the right paracolic gutter
  • Transcoelomic spread of malignancy, seeding the omentum, the diaphragm and the pouch of Douglas
  • Peritoneal dialysis, which relies on the surface area (about 1 to 2 square metres) and this absorptive capacity
  • Pleural effusion in ascites or Meigs syndrome, as fluid passes through diaphragmatic defects