Anatomy subcategory

Inborn Errors of Metabolism

Mnemonics for inherited metabolic disorders and the enzyme defects behind them.

Entries in Inborn Errors of Metabolism

Cystic Fibrosis Biochemistry Mnemonic

A defective chloride channel causes thick secretions in every exocrine organ

A memory aid for the molecular defect in cystic fibrosis.

Inborn Errors of MetabolismRespiratory Infection
G6PD Deficiency Mnemonic

Loss of NADPH leaves red cells defenceless against oxidative stress

A memory aid for glucose-6-phosphate dehydrogenase deficiency and its triggers.

Inborn Errors of Metabolism
Homocystinuria Mnemonic

Cystathionine beta synthase deficiency, resembling Marfan syndrome with thrombosis

A memory aid for the features of homocystinuria.

Inborn Errors of Metabolism
Lysosomal Storage Disorders Mnemonic

Enzyme deficiency causes substrate accumulation within lysosomes

A memory aid for the main lysosomal storage diseases.

Inborn Errors of Metabolism
Mitochondrial Disorders Mnemonic

Maternally inherited, affecting the most energy dependent tissues

A memory aid for the features and inheritance of mitochondrial disease.

Inborn Errors of Metabolism
Newborn Screening Conditions Mnemonic

Nine conditions in the UK programme, taken at day 5

A memory aid for the conditions detected on the newborn blood spot.

Inborn Errors of MetabolismTest Interpretation and Statistics
Organic Acidaemias and Urea Cycle Defects Mnemonic

Organic acidaemias cause acidosis with a raised anion gap; urea cycle defects cause alkalosis

A memory aid for distinguishing the two groups of metabolic crisis in neonates.

Inborn Errors of Metabolism
Phenylketonuria Mnemonic

Phenylalanine hydroxylase deficiency, so phenylalanine accumulates and tyrosine becomes essential

A memory aid for the biochemistry of phenylketonuria.

Inborn Errors of Metabolism
Wilson Disease and Haemochromatosis Mnemonic

Wilson accumulates copper; haemochromatosis accumulates iron

A memory aid for the two classic metal overload disorders.

Inborn Errors of Metabolism