Mnemonic

Rapid Sequence Induction

A mnemonic for the preparation and steps of rapid sequence induction.

Expansion

The seven Ps, from preparation to post-intubation management

Expansion

The seven Ps:

  • P - Preparation: drugs, suction, tilting trolley, monitoring, and a failed intubation plan
  • P - Pre-oxygenation, for 3 minutes or 8 vital capacity breaths
  • P - Pretreatment, where indicated
  • P - Paralysis with induction: an induction agent immediately followed by a muscle relaxant
  • P - Protection and positioning, with cricoid pressure if used
  • P - Placement with proof: waveform capnography
  • P - Post-intubation management: sedation, ventilation, tube securing, chest radiograph

Drugs: induction with ketamine (haemodynamically stable, useful in shock), propofol (causes hypotension) or etomidate; paralysis with suxamethonium (fast on and off, but avoided in hyperkalaemia, burns over 24 hours old, spinal injury and neuromuscular disease) or rocuronium (reversible with sugammadex).

“Capnography confirms the tube; nothing else does.” A sustained waveform over six breaths is the standard, and its absence in a perfusing patient means oesophageal intubation until proven otherwise.

Predict difficulty before starting, using LEMON: Look externally, Evaluate 3-3-2, Mallampati, Obstruction, Neck mobility.

Cricoid pressure is increasingly questioned, since it can worsen the laryngoscopic view, and it should be released if it impedes intubation.